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I loved this drug--until my insurance company said it was the 'same' as another less expensive drug. I've been miserable ever since. The acid reflux is returning, I am bloated and bowels are always a surprise. My surgeon is thinking a second surgery might be needed - if only I could afford the Protonix it could be avoided.
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Conclusions: as a result of the damage due to chronic gastroesoptmgeal reflux, pts can develop esophagitis or Barrett's esophagus.
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Additionally, in study 1, patients with a history of an acute life-threatening event (near-sudden infant death syndrome) suspected to be related to GERD were excluded.
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Coadministration of pantoprazole in healthy subjects and in transplant patients receiving MMF has been reported to reduce the exposure to the active metabolite, mycophenolic acid (MPA), possibly due to a decrease in MMF solubility at an increased gastric pH.
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